CX3CR1 (EL); RBX HU-100UG

Code: AB1891 D2-231

Application

Anti-C-X-X-X-C Chemokine Receptor 1 Antibody, extracellular loop is an antibody against C-X-X-X-C Chemokine Receptor 1 for use in IH & WB.

Western blot: 1:5...


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€457.00 EACH
€562.11 inc. VAT

Application

Anti-C-X-X-X-C Chemokine Receptor 1 Antibody, extracellular loop is an antibody against C-X-X-X-C Chemokine Receptor 1 for use in IH & WB.

Western blot: 1:500 (THP cell lysate can be used as positive control and an approximately 50 kDa band can be detected)

Immunohistochemistry in frozen sections

Optimal working dilutions must be determined by end user.

General description

CX3CR1 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human, mouse, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively (1-4). The seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1 (5). Recently, CX3CR1 was found to serve as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by facktokine (6). CX3CR1 mediates leukocyte migration and adhesion.

Immunogen

Synthetic peptide from the extracellular loop of human CX3CR1.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Format: Purified

antibody formpurified immunoglobulin
antibody product typeprimary antibodies
biological sourcerabbit
clonepolyclonal
Gene Informationhuman ... CX3CR1(1524)
manufacturer/tradenameChemicon®
NCBI accession no.NM_001337.3
Quality Level100
shipped inwet ice
species reactivityhuman
technique(s)western blot: suitable, immunohistochemistry: suitable
UniProt accession no.P49238
This product has met the following criteria to qualify for the following awards:



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